A solvent-free synthesis of polyhydroquinolines via Hantzsch multicomponent condensation catalyzed by nanomagnetic-supported sulfonic acid
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چکیده
منابع مشابه
MCM-BP as a Novel Nanomagnetic Reusable Basic Catalyst for the one Pot Solvent-Free Synthesis of Dihydropyridine, Polyhydroquinoline and Polyhydroacridine Derivatives via Hantzsch Multicomponent Condensation Reaction
By the immobilization of bipyridinium chloride onto mesoporous MCM-41encapsulated Fe3O4 nanoparticles via a simple post-synthesis method, a totally new organic-inorganic hybrid nanocomposite was formulated. The heterogeneous hybrid nanomagnetic composite was characterized by <spa...
متن کاملOne Pot Synthesis of Polyhydroquinolines Catalyzed by Sulfonic Acid Functionalized SBA-15 as a New Nanoporous Acid Catalyst under Solvent Free Conditions
Sulfonic acid functionalized SBA-15 (SBA-Pr-SO3H) as a new nanoporous acid catalyst was used in the one-pot synthesis of polyhydroquinolines derivatives via the Hantzsch four component condensation reaction of aldehydes, b-ketoesters, dimedone and ammonium acetate under solvent free conditions with short reaction time in excellent yields. SBA-P...
متن کاملSynthesis of Some Biginelli-type Products: Nano Alumina Sulfonic acid (NASA) Catalyzed under Solvent-free Condition
Biginelli-type reaction was developed by means of a three-component condensation of analdehyde, ethyl acetoacetate, urea or thiourea and nano alumina sulfonic acid (Al2O3-SO3H)(NASA) as catalyzed. It is carried out under different conditions. In all conditions, the desiredproducts are obtained in high yields after relatively short reaction times. Nevertheless, thereactions proceeded faster and ...
متن کاملone pot synthesis of polyhydroquinolines catalyzed by sulfonic acid functionalized sba-15 as a new nanoporous acid catalyst under solvent free conditions
sulfonic acid functionalized sba-15 (sba-pr-so3h) as a new nanoporous acid catalyst was used in the one-pot synthesis of polyhydroquinolines derivatives via the hantzsch four component condensation reaction of aldehydes, b-ketoesters, dimedone and ammonium acetate under solvent free conditions with short reaction time in excellent yields. sba-pr-so3h was proved to be an efficient heterogeneous ...
متن کاملEnantioselective organocatalytic Hantzsch synthesis of polyhydroquinolines.
The four-component Hantzsch reaction provides access to pharmaceutically important dihydropyridines. To expand the utility of this method, we have developed a route under organocatalytic conditions with good yields and excellent ee's. Through catalyst screening, we found that a BINOL-phosphoric acid allowed enantioselective synthesis of six-membered heterocycles with a variety of substitution p...
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ژورنال
عنوان ژورنال: South African Journal of Chemistry
سال: 2015
ISSN: 1996-840X
DOI: 10.17159/0379-4350/2015/v68a3